All SART Member Clinics
Last updated April 25, 2018
Final CSR for 2015
What is the difference between a Preliminary and Final CSR and why are some cycles delayed?
The outcome of a primary cycle for patients using their own eggs may be delayed if the retrieval occurred during the reporting year, but the outcome of the first embryo
transfer will not be known until the next reporting year. We are now accounting for treatment outcomes that are realized one year beyond the end of the reporting
year. Therefore the annual CSR will be labeled “preliminary” the first year it is posted and “final” the following year.
Patient’s Own Eggs
For women undergoing treatment with their own eggs, the end point of a treatment cycle can vary and this report attempts to capture the success rate following one or
more egg retrievals and the first embryo transfer (primary outcome), the success of subsequent cycles using frozen eggs or embryos not transferred in the first embryo
transfer and, finally, the combined contribution of the primary and subsequent cycles to the cumulative live birth rate for a patient.
If an embryo transfer occurred, the PRIMARY OUTCOME may be attributed to either a fresh or frozen embryo transfer. If you wish to review primary outcomes from fresh embryo transfers, use the FILTER feature and exclude frozen embryo transfers. If you wish to review primary outcomes from cycles where no fresh embryo transfer occurred and the outcome is from the 1st frozen embryo transfer, use the FILTER feature and include only frozen embryo transfers.
Final CSR for 2015
The Preliminary 2016 CSR is available. Click on FILTER above and select Reporting Year 2016 to view.
3660 Delayed Outcome cycles included
4989 cycles from 2016 were pulled back into 2015
3457 cycles from 2015 were pulled back into 2014
Total Cycles: 208076
Embryo Banking for Fertility Preservation: 3215
Oocyte Banking for Fertility Preservation: 7026
UNDERSTAND THIS REPORT
This report is completely re-designed from the past. We did this to provide patients with outcomes that reflect changes in the way infertility is treated through IVF. In recent years, there has been increased emphasis on embryo cryopreservation, genetic testing,
and single embryo transfer that was not adequately captured by the old reporting system. This report captures the treatment burden to the patient (the number of cycles) as well
as the best outcome (delivery of a healthy child) by tracking outcomes over time for an individual, accounting for both fresh and frozen embryo transfers. We hope this will
help you better understand the expected outcomes from Assisted Reproductive Technologies (ART). If you want to get a more personalized prognosis for your chances, please visit
the SART patient predictor.
The SART Clinic Summary Report (CSR) allows patients to view national and individual clinic IVF success rates. The data presented in this report should not be used for
comparing clinics. Clinics may have differences in patient selection and treatment approaches which may artificially inflate or lower pregnancy rates relative to another
clinic. Please discuss this with your doctor.
What is the difference between a Preliminary and Final CSR and why are some cycles delayed?What is a cycle?
A cycle is counted when a woman has started medications for the purpose of having an ART procedure. In the case of a “natural” cycle when no medications are used, the cycle starts with the first day of a woman’s menstrual cycle when she is planning to have an ART procedure done that month. The cycle is counted if an egg retrieval is performed or if the cycle is cancelled before the egg retrieval. If several cycles are performed to bank eggs or embryos, each will be counted in the denominator when calculating the pregnancy rate. For example, if three successive ovarian stimulation cycles are performed with the purpose of accumulating or “banking” embryos for one embryo transfer later that year that results in a delivery, the delivery rate would be 1/3 (33%). We feel that counting each cycle and not just focusing on the embryo transfer more accurately reflects the treatment burden and costs the patient has endured.
What is considered a “success”?
In this report, we have emphasized the delivery of a child (rather than a positive pregnancy test) as the main outcome of interest, since this is the outcome patients desire. We also have emphasized singleton deliveries since twin and higher order multiple pregnancies have a higher risk of premature delivery and have increased medical complications during the pregnancy and after delivery, often with infants requiring stays in the neonatal intensive care unit. Cycle success is measured by the live birth rate with a singleton delivery occurring after 37 weeks of gestation being the optimal outcome of IVF cycle. The percentage of triplet, twin and singleton births contributing to the live birth rate are provided for each cycle group and a summation of all deliveries (singletons and multiple births) is provided in the report. We have also reported the risk of premature delivery by dividing the live births into three groups including delivery occurring before 32 weeks of gestation (very pre-term), 32-37 weeks of gestation (pre-term) or reaching term (>37 weeks).
Outcomes are divided by several factors including patient age and source of the eggs whether autologous (originating from the female patient) or donor eggs. These are important prognostic factors and by separating the data, you can get a better idea of both national and individual clinic experience by these factors. The report contains additional filters for infertility diagnosis, stimulation type and other treatment details are available for patients to review the number of procedures and outcomes for specific patient groups and treatments.
Patient’s Own EggsStarting treatment
A cycle is initiated for egg retrieval. This cycle is concluded with the outcome of the first embryo transfer (fresh or frozen embryos) or it has been determined that embryo transfer will not be performed within a year of the egg retrieval cycle start. This endpoint is the PRIMARY OUTCOME. If an embryo transfer occurred, the PRIMARY OUTCOME may be attributed to either a fresh or frozen embryo transfer. If you wish to review primary outcomes from fresh embryo transfers, use the FILTER feature and exclude frozen embryo transfers. If you wish to review primary outcomes from cycles where no fresh embryo transfer occurred and the outcome is from the 1st frozen embryo transfer, use the FILTER feature and include only frozen embryo transfers.
Subsequent cycles
The subsequent cycle is any cycle involving the thawing of eggs or embryos after the PRIMARY OUTCOME has been determined. This is the cycle that is started either after the 1st embryo transfer has occurred or if more than one year has passed since the egg retrieval and this cycle is the first egg of embryo thaw. The endpoint is the SUBSEQUENT OUTCOME.
Cumulative Live Birth Rate
The cumulative live birth rate reflects the chance of achieving a live birth after a fresh or frozen embryo transfer within a year of cycle initiated for egg retrieval. The live birth may have been the PRIMARY OUTCOME (from the 1st fresh or frozen embryo transfer) or a SUBSEQUENT OUTCOME (frozen embryo transfers). The 2014 reporting year was the first year that subsequent cycles were linked to the egg retrieval cycles to generate the cumulative outcome or CUMULATIVE LIVE BIRTH RATE per egg retrieval cycle.
Live Birth Rate per Patient
The live birth rate per patient includes the outcomes for patients who are new to an infertility center and starting their first cycle for retrieval of their own eggs during the reporting year.
PATIENT'S OWN EGGS
FINAL CUMULATIVE OUTCOME PER EGG RETRIEVAL CYCLE
| Age of woman | |||||
|---|---|---|---|---|---|
| < 35 | 35 - 37 | 38 - 40 | 41 - 42 | > 42 | |
| Number of cycle starts | 43639 | 23183 | 22290 | 11603 | 8175 |
| Singletons | 42.4 % | 32.7 % | 21.9 % | 11.1 % | 3.6 % |
| Twins | 11.2 % | 7.4 % | 4.0 % | 1.5 % | 0.3 % |
| Triplets or more | 0.3 % | 0.2 % | 0.1 % | 0.0 % | 0 % |
| Live Births | 53.9 % | 40.2 % | 26.0 % | 12.6 % | 3.9 % |
| (Confidence Range) | (53.4 - 54.3) | (39.6 - 40.9) | (25.4 - 26.5) | (12.0 - 13.2) | (3.5 - 4.3) |
| Term | 78.3 % | 79.7 % | 80.7 % | 82.1 % | 83.5 % |
| Pre-term | 17.6 % | 16.5 % | 16.0 % | 14.5 % | 14.6 % |
| Very pre-term | 4.1 % | 3.8 % | 3.3 % | 3.4 % | 1.9 % |
| Very pre-term births | N | |
| Pre-term births | N | |
| Term births | N |
| Triplet births | N | |
| Twin births | N | |
| Singleton births | N |
| Age of woman | |||||
|---|---|---|---|---|---|
| < 35 | 35 - 37 | 38 - 40 | 41 - 42 | > 42 | |
| Mean # of transfers for patients achieving live birth | 1.28 | 1.24 | 1.18 | 1.10 | 1.07 |
PATIENT'S OWN EGGS
FINAL PRIMARY OUTCOME PER EGG RETRIEVAL CYCLE
| Age of woman | |||||
|---|---|---|---|---|---|
| < 35 | 35 - 37 | 38 - 40 | 41 - 42 | > 42 | |
| Number of cycle starts | 43601 | 23152 | 22259 | 11582 | 8171 |
| Singletons | 32.8 % | 25.9 % | 18.2 % | 9.8 % | 3.3 % |
| Twins | 8.7 % | 6.1 % | 3.5 % | 1.3 % | 0.3 % |
| Triplets or more | 0.2 % | 0.1 % | 0.1 % | 0.0 % | 0 % |
| Live Births | 41.7 % | 32.2 % | 21.8 % | 11.1 % | 3.6 % |
| (Confidence Range) | (41.3 - 42.2) | (31.6 - 32.8) | (21.2 - 22.3) | (10.6 - 11.7) | (3.2 - 4.0) |
| Term | 78.4 % | 79.7 % | 80.4 % | 81.9 % | 83.7 % |
| Pre-term | 17.7 % | 16.5 % | 16.2 % | 14.6 % | 14.6 % |
| Very pre-term | 3.9 % | 3.8 % | 3.4 % | 3.6 % | 1.7 % |
| Very pre-term births | N | |
| Pre-term births | N | |
| Term births | N |
| Triplet births | N | |
| Twin births | N | |
| Singleton births | N |
Select # embryos transferred:
| Age of woman | |||||
|---|---|---|---|---|---|
| < 35 | 35 - 37 | 38 - 40 | 41 - 42 | > 42 | |
| Number of cycle starts | 43601 | 23152 | 22259 | 11582 | 8171 |
| Number of retrievals | 41154 | 21189 | 19734 | 9918 | 6720 |
| Cancelled cycles | 5.6 % | 8.5 % | 11.3 % | 14.4 % | 17.8 % |
| Retrievals with no embryos suitable for transfer | 4.5 % | 7.9 % | 12.6 % | 20.2 % | 27.3 % |
| Mean number of embryos transferred | 1.5 | 1.6 | 1.9 | 2.2 | 2.5 |
| eSET % (elective Single Embryo Transfer) | 41.6 % | 31.8 % | 21.8 % | 14.0 % | 9.4 % |
| Age of woman | |||||
|---|---|---|---|---|---|
| < 35 | 35 - 37 | 38 - 40 | 41 - 42 | > 42 | |
| Number of cycle starts | 43601 | 23152 | 22259 | 11582 | 8171 |
| Positive pregnancy test | 56.6 % | 46.8 % | 34.7 % | 22.0 % | 10.1 % |
| Clinical pregnancies | 48.3 % | 39.1 % | 28.3 % | 16.5 % | 6.8 % |
| Miscarriage rate | 12.1 % | 15.8 % | 20.8 % | 29.9 % | 45.0 % |
| Number of retrievals | 41154 | 21189 | 19734 | 9918 | 6720 |
| Live birth per retrieval | 44.2 % | 35.2 % | 24.6 % | 13.0 % | 4.4 % |
| Positive pregnancy test | 59.9 % | 51.1 % | 39.1 % | 25.6 % | 12.3 % |
| Clinical pregnancies | 51.2 % | 42.8 % | 31.9 % | 19.3 % | 8.2 % |
| Number of transfers | 36758 | 17402 | 14222 | 5842 | 3325 |
| Live birth per transfer | 49.5 % | 42.8 % | 34.1 % | 22.0 % | 8.8 % |
| Positive pregnancy test | 67.1 % | 62.2 % | 54.3 % | 43.4 % | 24.8 % |
| Clinical pregnancies | 57.3 % | 52.1 % | 44.2 % | 32.7 % | 16.6 % |
| Implantation rate | 44.4 % | 36.6 % | 26.0 % | 14.6 % | 5.8 % |
PATIENT'S OWN EGGS
FINAL SUBSEQUENT OUTCOME (FROZEN CYCLES)
| Age of woman | |||||
|---|---|---|---|---|---|
| < 35 | 35 - 37 | 38 - 40 | 41 - 42 | > 42 | |
| Number of thaw procedures | 17646 | 9224 | 6334 | 2240 | 1483 |
| Singletons | 35.8 % | 33.6 % | 30.0 % | 26.3 % | 23.4 % |
| Twins | 8.4 % | 6.4 % | 4.8 % | 3.7 % | 2.0 % |
| Triplets or more | 0.2 % | 0.1 % | 0.1 % | 0.1 % | 0 % |
| Live births | 44.4 % | 40.1 % | 35.0 % | 30.1 % | 25.4 % |
| (Confidence Range) | (43.6 - 45.1) | (39.1 - 41.1) | (33.8 - 36.2) | (28.2 - 32.0) | (23.1 - 27.6) |
| Term | 79.0 % | 82.4 % | 82.3 % | 84.1 % | 85.4 % |
| Pre-term | 17.0 % | 14.5 % | 15.0 % | 13.6 % | 11.7 % |
| Very pre-term | 4.0 % | 3.1 % | 2.7 % | 2.2 % | 2.9 % |
| Very pre-term births | N | |
| Pre-term births | N | |
| Term births | N |
| Triplet births | N | |
| Twin births | N | |
| Singleton births | N |
Select # embryos transferred:
| Age of woman | |||||
|---|---|---|---|---|---|
| < 35 | 35 - 37 | 38 - 40 | 41 - 42 | > 42 | |
| Number of cycle starts | 19152 | 10206 | 7106 | 2603 | 1775 |
| Cancelled cycles | 1506 | 982 | 772 | 363 | 292 |
| Number of thaw procedures | 17646 | 9224 | 6334 | 2240 | 1483 |
| Thaw procedures with no embryos suitable for transfer | 182 | 100 | 94 | 31 | 55 |
| Mean number of embryos transferred | 1.5 | 1.5 | 1.5 | 1.6 | 1.7 |
| eSET % (elective Single Embryo Transfer) | 39.3 % | 38.6 % | 32.6 % | 30.6 % | 24.4 % |
| Age of woman | |||||
|---|---|---|---|---|---|
| < 35 | 35 - 37 | 38 - 40 | 41 - 42 | > 42 | |
| Positive pregnancy test | 64.9 % | 61.6 % | 57.2 % | 51.3 % | 46.3 % |
| Clinical pregnancies | 53.8 % | 50.3 % | 46.3 % | 40.7 % | 37.0 % |
| Miscarriage rate | 15.8 % | 18.5 % | 22.4 % | 24.3 % | 29.7 % |
| Implantation rate | 41.2 % | 37.6 % | 32.4 % | 26.4 % | 22.2 % |
PATIENT'S OWN EGGS
FINAL LIVE BIRTH PER NEW PATIENT
| Age of woman | |||||
|---|---|---|---|---|---|
| < 35 | 35 - 37 | 38 - 40 | 41 - 42 | > 42 | |
| Number of patients | 32569 | 14672 | 12315 | 5510 | 3510 |
| Singletons | 54.3 % | 46.0 % | 34.7 % | 19.2 % | 5.9 % |
| Twins | 14.0 % | 10.4 % | 6.0 % | 2.2 % | 0.5 % |
| Triplets or more | 0.3 % | 0.2 % | 0.2 % | 0.1 % | 0 % |
| Live Births | 68.6 % | 56.5 % | 40.8 % | 21.5 % | 6.3 % |
| (Confidence Range) | (68.1 - 69.1) | (55.7 - 57.3) | (40.0 - 41.7) | (20.4 - 22.6) | (5.5 - 7.1) |
| Term | 78.4 % | 79.4 % | 80.6 % | 82.7 % | 84.7 % |
| Pre-term | 17.4 % | 16.7 % | 16.1 % | 13.8 % | 13.5 % |
| Very pre-term | 4.2 % | 3.9 % | 3.3 % | 3.6 % | 1.8 % |
| Very pre-term births | N | |
| Pre-term births | N | |
| Term births | N |
| Triplet births | N | |
| Twin births | N | |
| Singleton births | N |
| Age of woman | |||||
|---|---|---|---|---|---|
| < 35 | 35 - 37 | 38 - 40 | 41 - 42 | > 42 | |
| Mean # of attempts at egg retrieval for patients achieving live birth | 1.21 | 1.32 | 1.48 | 1.67 | 1.69 |
| Mean # of transfers for patients achieving live birth | 1.44 | 1.44 | 1.41 | 1.34 | 1.25 |
DONOR EGGS
FRESH DONOR EGGS
| Age of woman | |
|---|---|
| All ages | |
| Number of recipient cycle starts | 5874 |
| Singletons | 36.4 % |
| Twins | 13.7 % |
| Triplets or more | 0.2 % |
| Live births | 50.2 % |
| (Confidence Range) | (48.9 - 51.5) |
| Term | 71.7 % |
| Pre-term | 23.4 % |
| Very pre-term | 4.9 % |
| Very pre-term births | N | |
| Pre-term births | N | |
| Term births | N |
| Triplet births | N | |
| Twin births | N | |
| Singleton births | N |
Select # embryos transferred:
| Age of woman | |
|---|---|
| All ages | |
| Number of transfers | 5333 |
| Mean number of embryos transferred | 1.6 |
| eSET (elective Single Embryo Transfer) | 41.3 % |
DONOR EGGS
FROZEN DONOR EGGS
| Age of woman | |
|---|---|
| All ages | |
| Number of recipient cycle starts | 3165 |
| Singletons | 29.8 % |
| Twins | 8.3 % |
| Triplets or more | 0.2 % |
| Live births | 38.3 % |
| (Confidence Range) | (36.6 - 40.0) |
| Term | 71.1 % |
| Pre-term | 23.7 % |
| Very pre-term | 5.2 % |
| Very pre-term births | N | |
| Pre-term births | N | |
| Term births | N |
| Triplet births | N | |
| Twin births | N | |
| Singleton births | N |
Select # embryos transferred:
| Age of woman | |
|---|---|
| All ages | |
| Number of transfers | 2684 |
| Mean number of embryos transferred | 1.6 |
| eSET (elective Single Embryo Transfer) | 34.9 % |
DONOR EGGS
THAWED EMBRYOS
| Age of woman | |
|---|---|
| All ages | |
| Number of recipient cycle starts | 10949 |
| Singletons | 32.5 % |
| Twins | 6.7 % |
| Triplets or more | 0.1 % |
| Live births | 39.3 % |
| (Confidence Range) | (38.4 - 40.2) |
| Term | 76.0 % |
| Pre-term | 19.8 % |
| Very pre-term | 4.2 % |
| Very pre-term births | N | |
| Pre-term births | N | |
| Term births | N |
| Triplet births | N | |
| Twin births | N | |
| Singleton births | N |
Select # embryos transferred:
| Age of woman | |
|---|---|
| All ages | |
| Number of transfers | 10134 |
| Mean number of embryos transferred | 1.4 |
| eSET (elective Single Embryo Transfer) | 44.1 % |
DONATED EMBRYOS
| Age of woman | |
|---|---|
| All ages | |
| Number of recipient cycle starts | 1405 |
| Singletons | 29.9 % |
| Twins | 7.8 % |
| Triplets or more | 0.3 % |
| Live births | 37.9 % |
| (Confidence Range) | (35.4 - 40.5) |
| Term | 71.9 % |
| Pre-term | 23.3 % |
| Very pre-term | 4.9 % |
| Very pre-term births | N | |
| Pre-term births | N | |
| Term births | N |
| Triplet births | N | |
| Twin births | N | |
| Singleton births | N |
Select # embryos transferred:
| Age of woman | |
|---|---|
| All ages | |
| Number of transfers | 1329 |
| Mean number of embryos transferred | 1.7 |
| eSET (elective Single Embryo Transfer) | 24.5 % |
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